| ncRNA name | hsa-miR-302d-3p |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | RPE cell lines hiPSC-RPE and ARPE-19; human umbilical vein endothelial cells (HUVECs) |
| Methods | RT-PCR, qPCR, immunoblotting, immunofluorescence, apoptosis assay, proliferation and migration assay, luciferase reporter assay, ELISA, tube formation assay |
| Expression pattern | up-regulated |
| Functional description | miR-302d-3p promotes RPE dedifferentiation, migration, proliferation and cell-cycle progression, inhibits RPE phagocytosis, and induces abnormal EC behavior by targeting p21Waf1/Cip1. |
| PubMed ID | 29670082 |
| Year | 2018 |
| Title | c-Jun-mediated microRNA-302d-3p induces RPE dedifferentiation by targeting p21Waf1/Cip1. |
| Drug-related ncRNA | NO |
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